INT173117

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Context Info
Confidence 0.12
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.85
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ltf) transport (Ltf) extracellular region (Ltf)
cytoplasm (Ltf)
Ltf (Mus musculus)
Pain Link Frequency Relevance Heat
cva 3 89.88 High High
Inflammation 26 86.00 High High
cytokine 38 84.96 Quite High
agonist 12 5.00 Very Low Very Low Very Low
chemokine 8 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 1 98.44 Very High Very High Very High
Herpes Simplex Virus 1 93.12 High High
Disease 7 91.76 High High
Granuloma 22 91.04 High High
Sprains And Strains 52 90.68 High High
Hemorrhage 3 89.88 High High
Pneumonia 50 87.52 High High
Cyst 7 86.92 High High
INFLAMMATION 34 86.00 High High
Death 4 84.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
as a key mediator in the stimulation of hepatocellular proliferation, recent findings suggest that down-regulation of the iron-binding protein lactoferrin (LF) upon PP treatment may play a role in initiating the growth response [90].
lactoferrin Binding (binding) of
1) Confidence 0.12 Published 2003 Journal Comp Hepatol Section Body Doc Link PMC151270 Disease Relevance 0.20 Pain Relevance 0.12
This study characterizes the HTL epitopes of a candidate pneumococcal vaccine antigen, PspA, which is a highly conserved, cell wall-associated surface protein that plays a major role in pneumococcal virulence by binding human lactoferrin and interferes with complement deposition on the bacterial surface [5].
lactoferrin Binding (binding) of
2) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2828482 Disease Relevance 0.52 Pain Relevance 0.03
Sequestration of the scarce quantities of soluble iron is a prototypical protective response against invading bacteria, mediated by the iron-binding proteins transferrin and lactoferrin and the storage protein ferritin.
lactoferrin Binding (binding) of
3) Confidence 0.06 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2757716 Disease Relevance 0 Pain Relevance 0
Sade [8] suggested an alternative theory in 1979, emphasizing the role of low ventilation and hypoxia implying that cholesterol derives from disintegrated tissue and that iron is associated with lactoferrin.
lactoferrin Binding (associated) of associated with hypoxia
4) Confidence 0.03 Published 2010 Journal BMC Ear Nose Throat Disord Section Body Doc Link PMC2853487 Disease Relevance 1.12 Pain Relevance 0.14

General Comments

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