INT173130

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Context Info
Confidence 0.04
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.80
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (INS, PPARA) nucleoplasm (PPARA) DNA binding (PPARA)
carbohydrate metabolic process (INS) lipid metabolic process (PPARA) cell-cell signaling (INS)
INS (Homo sapiens)
PPARA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 8 100.00 Very High Very High Very High
Inflammatory response 2 62.40 Quite High
agonist 45 50.00 Quite Low
cINOD 4 42.56 Quite Low
cytokine 10 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 25 100.00 Very High Very High Very High
INFLAMMATION 13 100.00 Very High Very High Very High
Obesity 49 99.82 Very High Very High Very High
Hyperlipidemia 1 85.20 High High
Hyperglycemia 2 74.12 Quite High
Disorder Of Lipid Metabolism 6 72.28 Quite High
Insulin Resistance 7 52.56 Quite High
Apoptosis 55 50.00 Quite Low
Tuberous Sclerosis 1 11.20 Low Low
Cancer 26 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PPAR ligands can be both synthetic, such as peroxisome proliferators, hypolipidaemic drugs, anti-inflammatory or insulin-sensitizing drugs, or endogenous, most of them being fatty acids or their derivatives.
insulin Binding (ligands) of PPAR associated with inflammation
1) Confidence 0.04 Published 2003 Journal Comp Hepatol Section Body Doc Link PMC151270 Disease Relevance 0.37 Pain Relevance 0.05
Accordingly, Auboeuf et al. [51] demonstrated that obesity and non-insulin-dependent diabetes mellitus are not associated with alteration in PPAR?
insulin Binding (associated) of PPAR associated with diabetes mellitus and obesity
2) Confidence 0.02 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 1.44 Pain Relevance 0.03

General Comments

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