INT173162

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Context Info
Confidence 0.80
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 22
Total Number 22
Disease Relevance 11.09
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (PPARA) nucleoplasm (PPARA) small molecule metabolic process (PPARA)
nucleus (PPARA) DNA binding (PPARA) lipid metabolic process (PPARA)
Anatomy Link Frequency
Adipose tissue 1
PPARA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 196 98.40 Very High Very High Very High
Inflammatory response 26 95.04 Very High Very High Very High
agonist 307 93.72 High High
Spinal cord 4 82.04 Quite High
cytokine 37 66.76 Quite High
COX2 2 50.00 Quite Low
cINOD 48 49.96 Quite Low
Potency 6 35.84 Quite Low
antagonist 19 18.64 Low Low
rheumatoid arthritis 10 9.76 Low Low
Disease Link Frequency Relevance Heat
Obesity 245 99.98 Very High Very High Very High
Gastrointestinal Neoplasms 11 99.60 Very High Very High Very High
Apoptosis 405 99.04 Very High Very High Very High
Cancer 723 98.84 Very High Very High Very High
INFLAMMATION 239 98.40 Very High Very High Very High
Colon Cancer 166 96.40 Very High Very High Very High
Glioblastoma 29 96.04 Very High Very High Very High
Death 56 94.76 High High
Metastasis 59 94.52 High High
Hypertrophy 4 94.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A group of PPAR?
Phosphorylation (group) of PPAR
1) Confidence 0.80 Published 2010 Journal PPAR Research Section Body Doc Link PMC2841252 Disease Relevance 1.99 Pain Relevance 0.03
Adipose tissue targets of PPAR?
Phosphorylation (targets) of PPAR in Adipose tissue associated with obesity
2) Confidence 0.73 Published 2010 Journal PPAR Research Section Body Doc Link PMC2825651 Disease Relevance 0.62 Pain Relevance 0.03
Whereas serine phosphorylation of PPAR?
Phosphorylation (phosphorylation) of PPAR
3) Confidence 0.70 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408681 Disease Relevance 0.07 Pain Relevance 0
particular those of PPAR?
Phosphorylation (those) of PPAR
4) Confidence 0.70 Published 2008 Journal PPAR Research Section Body Doc Link PMC2490577 Disease Relevance 0.85 Pain Relevance 0.41
The first evidence for the involvement of PPAR?
Phosphorylation (involvement) of PPAR
5) Confidence 0.70 Published 2008 Journal PPAR Research Section Body Doc Link PMC2490577 Disease Relevance 0.95 Pain Relevance 0.46
There are three isoforms of PPAR?
Phosphorylation (isoforms) of PPAR
6) Confidence 0.68 Published 2003 Journal Comp Hepatol Section Body Doc Link PMC151270 Disease Relevance 0.13 Pain Relevance 0
However, the role of PPAR?
Phosphorylation (role) of PPAR
7) Confidence 0.67 Published 2009 Journal PPAR Research Section Abstract Doc Link PMC2770108 Disease Relevance 0.72 Pain Relevance 0.08
MAPK/ERK-mediated phosphorylation of Ser84/112 on PPAR?
Phosphorylation (phosphorylation) of PPAR
8) Confidence 0.61 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408681 Disease Relevance 0.07 Pain Relevance 0
A summary of PPAR?
Phosphorylation (summary) of PPAR
9) Confidence 0.61 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464751 Disease Relevance 0.38 Pain Relevance 0
A summary of PPAR?
Phosphorylation (summary) of PPAR
10) Confidence 0.61 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408681 Disease Relevance 0.14 Pain Relevance 0
review summarizes the latest knowledge of the role of PPAR-?
Phosphorylation (role) of PPAR
11) Confidence 0.58 Published 2008 Journal PPAR Research Section Body Doc Link PMC2366048 Disease Relevance 1.46 Pain Relevance 0
The correlation of PPAR?
Phosphorylation (correlation) of PPAR
12) Confidence 0.58 Published 2010 Journal PPAR Research Section Body Doc Link PMC2933910 Disease Relevance 0.05 Pain Relevance 0.15
In rodents, long-term administration of PPAR?
Phosphorylation (administration) of PPAR
13) Confidence 0.58 Published 2010 Journal PPAR Research Section Body Doc Link PMC2933910 Disease Relevance 1.05 Pain Relevance 0.03
of PPAR phosphorylation may also support the antitumor function of these
Phosphorylation (phosphorylation) of PPAR
14) Confidence 0.55 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408709 Disease Relevance 0.22 Pain Relevance 0.15
via phosphorylation of the conserved MAP-kinase sites Ser12 and Ser21 in the A/B domain [12,13], whereas MAP-kinase mediated phosphorylation of Ser112 of mouse PPAR?
Phosphorylation (phosphorylation) of PPAR
15) Confidence 0.53 Published 2003 Journal Comp Hepatol Section Body Doc Link PMC151270 Disease Relevance 0.05 Pain Relevance 0
HER-kinase and its downstream ERK/MAPK pathway phosphorylate PPAR?
Phosphorylation (phosphorylate) of PPAR
16) Confidence 0.48 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408709 Disease Relevance 0.34 Pain Relevance 0
This inhibitory complex is adipogenesis stage-dependent, such that earlier in adipogenesis (i.e., at Day 4), hyperphosphorylation of RB minimizes complex formation (thus enabling maximal PPAR?
Phosphorylation (hyperphosphorylation) of PPAR
17) Confidence 0.44 Published 2009 Journal PPAR Research Section Body Doc Link PMC2830574 Disease Relevance 0.39 Pain Relevance 0.03
phosphorylation and inactivation of PPAR?
Phosphorylation (phosphorylation) of PPAR
18) Confidence 0.23 Published 2008 Journal PPAR Research Section Body Doc Link PMC2605846 Disease Relevance 0.70 Pain Relevance 0
affects phosphorylation and renders PPAR?
Phosphorylation (phosphorylation) of PPAR
19) Confidence 0.15 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943117 Disease Relevance 0.49 Pain Relevance 0
Phosphorylation of human PPAR?
Phosphorylation (Phosphorylation) of PPAR
20) Confidence 0.15 Published 2008 Journal PPAR Research Section Body Doc Link PMC2528242 Disease Relevance 0 Pain Relevance 0

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