INT173293

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Context Info
Confidence 0.03
First Reported 2003
Last Reported 2003
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (LPA) transport (LPA) small molecule metabolic process (LPA)
extracellular region (LPA) plasma membrane (OR1S1) signal transducer activity (OR1S1)
LPA (Homo sapiens)
OR1S1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 114 94.92 High High
Kinase C 36 91.52 High High
Morphine 2 57.28 Quite High
tolerance 4 56.80 Quite High
Opioid 4 55.72 Quite High
Inflammation 22 5.00 Very Low Very Low Very Low
bradykinin 20 5.00 Very Low Very Low Very Low
cytokine 16 5.00 Very Low Very Low Very Low
adenocard 16 5.00 Very Low Very Low Very Low
Catecholamine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bordatella Infection 4 75.00 Quite High
Asthma 86 5.00 Very Low Very Low Very Low
INFLAMMATION 24 5.00 Very Low Very Low Very Low
Disease 20 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 18 5.00 Very Low Very Low Very Low
Bronchospasm 4 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Airway Remodeling 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the contrary, transactivation of the EGF receptor is not induced by thrombin, carbachol, or LPA in human ASM cultures, and increased p42/p44 MAPK signaling does not appear to mediate the synergistic effect of several GPCR agonists on EGF-stimulated ASM growth [18,19].
LPA Positive_regulation (transactivation) of or is associated with agonist
1) Confidence 0.03 Published 2003 Journal Respir Res Section Body Doc Link PMC152647 Disease Relevance 0.07 Pain Relevance 0.23
On the contrary, transactivation of the EGF receptor is not induced by thrombin, carbachol, or LPA in human ASM cultures, and increased p42/p44 MAPK signaling does not appear to mediate the synergistic effect of several GPCR agonists on EGF-stimulated ASM growth [18,19].
LPA Neg (not) Positive_regulation (induced) of or is associated with agonist
2) Confidence 0.03 Published 2003 Journal Respir Res Section Body Doc Link PMC152647 Disease Relevance 0.07 Pain Relevance 0.23

General Comments

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