INT173358

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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gnaq, SMPD1) small molecule metabolic process (SMPD1) GTPase activity (Gnaq)
protein complex (Gnaq) signal transducer activity (Gnaq) cytosol (Gnaq)
Gnaq (Mus musculus)
SMPD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 10 89.28 High High
Kinase C 18 81.36 Quite High
agonist 57 79.52 Quite High
adenocard 8 48.16 Quite Low
Inflammation 11 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Catecholamine 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 43 70.16 Quite High
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 9 5.00 Very Low Very Low Very Low
Bronchospasm 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Airway Remodeling 2 5.00 Very Low Very Low Very Low
Bordatella Infection 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This suggests that effectors other than PLC can be directly activated by Gq in ASM.


Gq Positive_regulation (activated) of ASM
1) Confidence 0.01 Published 2003 Journal Respir Res Section Body Doc Link PMC152647 Disease Relevance 0.13 Pain Relevance 0.23

General Comments

This test has worked.

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