INT173403

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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.15
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgam) Golgi apparatus (GPER) endoplasmic reticulum (GPER)
nucleus (Itgam) plasma membrane (GPER) signal transducer activity (GPER)
Anatomy Link Frequency
internal 2
neutrophils 2
GPER (Homo sapiens)
Itgam (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 51 86.32 High High
halothane 12 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Catecholamine 6 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
Nerve growth factor 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 57 86.32 High High
Hypersensitivity 9 60.60 Quite High
Infection 6 33.92 Quite Low
Adhesions 63 29.16 Quite Low
Asthma 9 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Salivary Gland Disease 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Anaphylaxis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Figure 6 shows that feG reduced binding of CD11b antibody to the cell surface, whereas binding to the internal pool of this marker was not altered.
feG Negative_regulation (reduced) of CD11b Binding (binding) of in internal
1) Confidence 0.01 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0 Pain Relevance 0
The peptide feG reduced basal binding of CD11b to 896 ± 183 and 158 ± 29 for the peritoneal and blood neutrophils, respectively.
feG Negative_regulation (reduced) of CD11b Binding (binding) of in neutrophils
2) Confidence 0.01 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0.15 Pain Relevance 0.04
The reduction by feG of antibody binding for CD11b and CD16b could be due to several factors which include, preventing the mobilization of granule-stored intracellular molecules, promoting their shedding from the cell surface, or altering antibody binding without affecting the amount of CD11b or CD16b expressed on the cell membrane.
feG Negative_regulation (reduction) of CD11b Binding (binding) of
3) Confidence 0.01 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0 Pain Relevance 0

General Comments

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