INT173407

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Context Info
Confidence 0.01
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.26
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgam) Golgi apparatus (GPER) endoplasmic reticulum (GPER)
nucleus (Itgam) plasma membrane (GPER) signal transducer activity (GPER)
Anatomy Link Frequency
neutrophils 1
GPER (Homo sapiens)
Itgam (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 51 75.24 Quite High
Catecholamine 6 20.96 Low Low
halothane 12 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
Nerve growth factor 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 57 75.24 Quite High
Hypersensitivity 9 72.00 Quite High
Infection 6 56.00 Quite High
Adhesions 63 7.12 Low Low
Asthma 9 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Salivary Gland Disease 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Anaphylaxis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The inhibitory effect of feG, seen on the binding of CD11b under basal conditions for both circulating and peritoneal cells, was not observed in rats that received an antigen challenge 24 h previously.
feG Binding (binding) of CD11b
1) Confidence 0.01 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0.19 Pain Relevance 0.06
Since feG was synthesized based on the sequence of a rat peptide [5], but has potent activities on human neutrophils, we also examined the effects of this peptide on circulating rat neutrophils. feG at concentrations from 10-11M to 10-10M inhibited the binding of CD11b antibody to rat neutrophils (Figure 8).
feG Binding (binding) of CD11b in neutrophils
2) Confidence 0.01 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0.07 Pain Relevance 0
This result implies that feG alters primarily the binding of antibody to CD11b molecules located on the surface of cells.
feG Binding (alters) of CD11b
3) Confidence 0.01 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

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