INT173422

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Context Info
Confidence 0.45
First Reported 2002
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 11
Total Number 13
Disease Relevance 5.78
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ETFDH) mitochondrion (ETFDH) small molecule metabolic process (ETFDH)
oxidoreductase activity (ETFDH)
ETFDH (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 71 98.60 Very High Very High Very High
Morphine 3 98.32 Very High Very High Very High
pruritus 4 76.80 Quite High
depression 13 71.68 Quite High
Pain scale 5 5.00 Very Low Very Low Very Low
peripheral neuropathy 4 5.00 Very Low Very Low Very Low
halothane 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
antiepileptic Drug 2 5.00 Very Low Very Low Very Low
positron emission tomography 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dementia 98 99.84 Very High Very High Very High
Reprotox - General 1 72 99.84 Very High Very High Very High
Disease 98 99.44 Very High Very High Very High
Pain 75 98.60 Very High Very High Very High
Cancer 50 98.08 Very High Very High Very High
Sprains And Strains 9 91.60 High High
Diarrhoea 11 91.52 High High
Constipation 4 91.00 High High
Sleep Disorders 8 90.44 High High
Muscle Weakness 20 89.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, mutations can result in dysfunction of electron transfer flavoprotein (ETF) or ETF-ubiquinone oxidoreductase (ETF-QO).
Gene_expression (dysfunction) of ETF-ubiquinone oxidoreductase
1) Confidence 0.45 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2877206 Disease Relevance 0.52 Pain Relevance 0
Therefore, mutations can result in dysfunction of electron transfer flavoprotein (ETF) or ETF-ubiquinone oxidoreductase (ETF-QO).
Gene_expression (dysfunction) of ETF-QO
2) Confidence 0.45 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2877206 Disease Relevance 0.52 Pain Relevance 0
Predictors of QoL in prostate cancer patients
Gene_expression (Predictors) of QoL associated with reprotox - general 1
3) Confidence 0.43 Published 2010 Journal GMS Psycho-Social-Medicine Section Body Doc Link PMC2899861 Disease Relevance 1.21 Pain Relevance 0.19
This study revealed that patients with advanced prostate cancer retrospectively lowered their QoL scores at both the 3 and 6-month visits.
Gene_expression (scores) of QoL associated with reprotox - general 1
4) Confidence 0.34 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1079917 Disease Relevance 0.31 Pain Relevance 0
Whilst this was consistent with our initial hypothesis, it was also noted that partners in some cases demonstrated significantly worse QoL scores than the patients (particularly on the General Cancer Distress scale).
Gene_expression (scores) of QoL associated with cancer
5) Confidence 0.34 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1079917 Disease Relevance 0.38 Pain Relevance 0
There was no significant difference between QoL scores of both groups before the intervention, which was verified by Mann-Whitney test (P = 0.75).
Gene_expression (scores) of QoL
6) Confidence 0.27 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1156929 Disease Relevance 0.78 Pain Relevance 0.10
Crippen argues that these new therapies have forced the QoL issue and lobbies in favour of strict inclusion criteria based openly on QoL determinations.
Gene_expression (issue) of QoL
7) Confidence 0.27 Published 2002 Journal Crit Care Section Body Doc Link PMC153428 Disease Relevance 0 Pain Relevance 0
The Quality of Life in Alzheimer's Disease (QoL-AD) scale was used to measure QoL by self and informant reports.[5], [10] The 13 item QoL-AD scale is a widely used, brief (generally administered in ?
Gene_expression (measure) of QoL associated with disease
8) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001486 Disease Relevance 0.74 Pain Relevance 0
A poor association of informant report with self report and direct observation has also been described in the assessment of pain in the RCF setting.17 Our data emphasise that the perspectives of PWD and their informants are not necessarily congruent and that factors affecting the relationship between informants and PWD may influence informants' perceptions of the QoL of PWD.
Gene_expression (perceptions) of QoL associated with pain and dementia
9) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001486 Disease Relevance 0.73 Pain Relevance 0.24
Determinants of QoL
Spec (Determinants) Gene_expression (Determinants) of QoL
10) Confidence 0.05 Published 2007 Journal J Cardiothorac Surg Section Body Doc Link PMC2146998 Disease Relevance 0.15 Pain Relevance 0.15
Spot 6 (Rv3028c) is an electron transfer flavoprotein alpha subunit.
Gene_expression (transfer) of electron
11) Confidence 0.03 Published 2010 Journal Proteome Sci Section Body Doc Link PMC2998474 Disease Relevance 0.16 Pain Relevance 0
Probable electron transfer flavoprotein alpha-subunit (fixb) was also highly conserved in mycobacteria and other microbes.


Gene_expression (transfer) of electron
12) Confidence 0.03 Published 2010 Journal Proteome Sci Section Body Doc Link PMC2998474 Disease Relevance 0.15 Pain Relevance 0.10
These protein spots were further identified as DnaK, 60 kDa chaperonin2, Malate dehydrogenase, Probable oxidoreductase, Electron transfer flavoprotein subunit alpha, Antigen 84, 14 kDa antigen and two hypothetical proteins by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (Table 1) and identity also confirmed by MS/MS (Table 2).
Gene_expression (transfer) of Electron
13) Confidence 0.03 Published 2010 Journal Proteome Sci Section Body Doc Link PMC2998474 Disease Relevance 0.14 Pain Relevance 0

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