INT173558

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Context Info
Confidence 0.00
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CTSK) extracellular space (CTSK) extracellular region (COL5A2)
molecular_function (COL5A2) lysosome (CTSK) cytoplasm (CTSK)
Anatomy Link Frequency
osteoclasts 2
CTSK (Homo sapiens)
COL5A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 58 82.56 Quite High
rheumatoid arthritis 15 71.12 Quite High
Inflammation 7 69.40 Quite High
Osteoarthritis 15 65.44 Quite High
cytokine 6 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 16 85.76 High High
Necrosis 2 80.32 Quite High
Cancer 10 79.96 Quite High
Rheumatoid Arthritis 15 71.12 Quite High
INFLAMMATION 8 69.40 Quite High
Osteoarthritis 16 65.44 Quite High
Calcification 7 44.32 Quite Low
Myositis 1 22.00 Low Low
Osteoporosis 4 15.84 Low Low
Arthritis 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cathepsin K is also produced by osteoclasts and plays a key role in the degradation of bone collagen.
Cathepsin K Positive_regulation (role) of Protein_catabolism (degradation) of collagen in osteoclasts
1) Confidence 0.00 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC154424 Disease Relevance 0.53 Pain Relevance 0.22

General Comments

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