INT173599

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Context Info
Confidence 0.06
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP1, Mmp1a) extracellular region (MMP1, Mmp1a) proteinaceous extracellular matrix (MMP1, Mmp1a)
Anatomy Link Frequency
cleavage 1
MMP1 (Homo sapiens)
Mmp1a (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 58 84.96 Quite High
Osteoarthritis 15 81.60 Quite High
rheumatoid arthritis 15 57.40 Quite High
Arthritis 5 46.48 Quite Low
Inflammation 7 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 5 86.32 High High
Osteoarthritis 16 81.60 Quite High
Disease 14 75.68 Quite High
Arthritis 16 67.56 Quite High
Rheumatoid Arthritis 15 57.40 Quite High
Arthropathy 4 18.12 Low Low
Hypercalcemia 16 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low
Apoptosis 9 5.00 Very Low Very Low Very Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One of these enzymes, Mcol-A, cleaves collagen at the specific cleavage site and occupies a position sytenic to the human MMP-1 locus at 11q22.
MMP-1 Binding (occupies) of Mcol-A in cleavage
1) Confidence 0.06 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC154424 Disease Relevance 0.50 Pain Relevance 0.15

General Comments

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