INT173625

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.17
First Reported 2003
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.05
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAPK14) nucleoplasm (MAPK14) signal transduction (MAPK14)
nucleus (MAPK14) response to stress (MAPK14) cytoplasm (MAPK14)
MAPK14 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 13 97.16 Very High Very High Very High
Eae 1 93.88 High High
antagonist 24 77.68 Quite High
cytokine 39 72.36 Quite High
chemokine 1 70.72 Quite High
Central nervous system 22 58.76 Quite High
Calcium channel 1 50.88 Quite High
adenocard 27 50.00 Quite Low
Analgesic 1 48.08 Quite Low
Opioid 1 36.16 Quite Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 97.24 Very High Very High Very High
INFLAMMATION 16 97.16 Very High Very High Very High
Osteoarthritis 4 90.04 High High
Amyloid Plaque 1 88.72 High High
Diabetic Retinopathy 2 85.24 High High
Dementia 1 84.64 Quite High
Disease 15 82.28 Quite High
Airway Remodeling 1 57.04 Quite High
Asthma 5 54.56 Quite High
Acute Erythroblastic Leukemia 1 52.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, clinical pathology results revealed the presence of activated p38?
Positive_regulation (activated) of Localization (presence) of p38
1) Confidence 0.17 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2604896 Disease Relevance 0.39 Pain Relevance 0.25
-N-ethyl-carboxamidoadenosine (NECA) induced interleukin-8 secretion through the involvement of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinase kinase and this effect was blocked by 3-isobutyl-8-pyrrolidinoxanthine (IPDX) suggesting a basis for the development of new antiasthmatic drugs [24–26].
Positive_regulation (induced) of Localization (secretion) of p38
2) Confidence 0.13 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2096665 Disease Relevance 0.43 Pain Relevance 0.18
Indeed, our recent studies have shown that activation of the p38, ERK, and JNK MAP kinases is required for the chondrogenic induction and maintenance of TGF-?
Positive_regulation (activation) of Localization (kinases) of p38
3) Confidence 0.07 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC154434 Disease Relevance 0.23 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox