INT173644

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Context Info
Confidence 0.15
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (LRP5) plasma membrane (LRP5)
Anatomy Link Frequency
osteoblast 2
LRP5 (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 2 11.32 Low Low
cytokine 4 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 8 98.92 Very High Very High Very High
Syndrome 3 95.00 High High
Disease 4 85.12 High High
Obesity 7 5.00 Very Low Very Low Very Low
Adhesions 5 5.00 Very Low Very Low Very Low
Familial Adenomatous Polyposis 4 5.00 Very Low Very Low Very Low
Osteoarthritis 4 5.00 Very Low Very Low Very Low
Hematological Disease 3 5.00 Very Low Very Low Very Low
Focal Cartilage Defect 3 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has also been shown that mice with targeted disruptions of LRP-5 expression have a decreased level of osteoblast proliferation and display a phenotype similar to humans with osteoporosis–pseudoglioma syndrome [69].
Negative_regulation (disruptions) of Gene_expression (expression) of LRP-5 in osteoblast associated with syndrome and osteoporosis
1) Confidence 0.15 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC154434 Disease Relevance 0.59 Pain Relevance 0

General Comments

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