INT173648

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Context Info
Confidence 0.03
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (TFAP2A) nucleolus (TFAP2A) nucleus (TFAP2A)
cytoplasm (TFAP2A)
Anatomy Link Frequency
proximal 2
TFAP2A (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 5 95.88 Very High Very High Very High
Familial Adenomatous Polyposis 4 89.40 High High
Focal Cartilage Defect 3 28.40 Quite Low
Osteoarthritis 4 14.16 Low Low
Osteoporosis 8 5.00 Very Low Very Low Very Low
Obesity 7 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Hematological Disease 3 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At the level of transcriptional regulation, changes in the levels of cellular binding of the transcription factors Sp-1 and AP-2 to their cognate response DNA sequences contained within the proximal promoter region of the gene of a cartilage matrix component, aggrecan, are indeed the targets of TGF-?
Regulation (changes) of AP-2 Binding (binding) of in proximal
1) Confidence 0.03 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC154434 Disease Relevance 0.32 Pain Relevance 0

General Comments

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