INT173656

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Context Info
Confidence 0.57
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.23
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Cebpg) nucleus (Cebpg) DNA binding (Cebpg)
transcription factor binding (Cebpg)
Anatomy Link Frequency
RAW 264 1
Cebpg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 1 75.72 Quite High
Inflammation 26 72.64 Quite High
dexamethasone 2 72.32 Quite High
Nerve growth factor 17 61.80 Quite High
Inflammatory mediators 1 12.80 Low Low
Inflammatory response 2 12.72 Low Low
cytokine 8 8.52 Low Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 8 95.60 Very High Very High Very High
Stress 9 88.16 High High
Adverse Drug Reaction 30 82.96 Quite High
Diabetes Mellitus 12 79.20 Quite High
INFLAMMATION 24 75.52 Quite High
Hyperlipidemia 8 72.24 Quite High
Hyperlipoproteinemia Type Ii 5 70.32 Quite High
Apoptosis 8 66.00 Quite High
Neuroblastoma 3 56.24 Quite High
Dyslipidemia /

Combined Dyslipidemia

16 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reduction of solute carrier family 2, member 4 (SLC2A4) and CCAAT/enhancer binding protein (C/EBP) ?
Negative_regulation (Reduction) of C/EBP
1) Confidence 0.57 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2788597 Disease Relevance 0.49 Pain Relevance 0
It is believed that endogenous, canonical Wnt signaling maintains preadipocytes in an undifferentiated state by inhibiting C/EBP-?
Negative_regulation (inhibiting) of C/EBP
2) Confidence 0.42 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC154434 Disease Relevance 0.33 Pain Relevance 0.11
Consistent with our report, CO has been shown to down-regulate LPS-induced COX-2 expression and PGE2 secretion by inhibiting CCAAT/enhancer-binding protein (C/EBP) in LPS-treated RAW 264.7 cells [36].
Negative_regulation (inhibiting) of C/EBP in RAW 264
3) Confidence 0.42 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC3002338 Disease Relevance 0.36 Pain Relevance 0.10
, the transcriptional activity of C/EBP and Ngn2 might be downregulated in PC12 (WT-Akt) cells but upregulated in PC12 (DN-Akt) cells.
Negative_regulation (downregulated) of C/EBP
4) Confidence 0.41 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2844376 Disease Relevance 0.06 Pain Relevance 0.03

General Comments

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