INT173660

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Context Info
Confidence 0.15
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

response to stress (Map2k6, MAPK8) cytoplasm (Map2k6, MAPK8) nucleus (Map2k6, MAPK8)
nucleoplasm (MAPK8) mitochondrion (MAPK8) cytosol (MAPK8)
Map2k6 (Mus musculus)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 74.92 Quite High
rheumatoid arthritis 1 57.00 Quite High
dexamethasone 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 8 90.24 High High
Arthritis 1 65.92 Quite High
Disease 4 61.80 Quite High
Rheumatoid Arthritis 1 57.00 Quite High
Osteoarthritis 4 32.00 Quite Low
Cleidocranial Dysplasia 1 18.28 Low Low
Obesity 7 5.00 Very Low Very Low Very Low
Adhesions 5 5.00 Very Low Very Low Very Low
Familial Adenomatous Polyposis 4 5.00 Very Low Very Low Very Low
Hematological Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Potential downstream targets of activated TAK1 include MKK4/JNKK and MKK3/MAPKK6, which directly activate c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively [95,96].
MAPKK6 Positive_regulation (activate) of c-Jun N-terminal kinase
1) Confidence 0.15 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC154434 Disease Relevance 0.27 Pain Relevance 0.07

General Comments

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