INT173749

Context Info Confidence 0.10 First Reported 2003 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.47 Pain Relevance 0.71

cell proliferation (Mki67) nucleolus (Mki67) nucleus (Mki67) intracellular (Mki67) molecular_function (Mki67) cellular_component (Mki67)

Mki67 (Rattus norvegicus)

Pain Link Frequency Relevance Heat fluoxetine 62 98.06 amygdala 118 97.14 depression 32 50.00 antidepressant 31 50.00 sSRI 8 5.00 Eae 5 5.00 antagonist 5 5.00 agonist 4 5.00 Hippocampus 4 5.00 long-term potentiation 1 5.00

Disease Link Frequency Relevance Heat Anxiety Disorder 91 100.00 Depression 33 50.00 Neurodegenerative Disease 24 5.00 Stress 9 5.00 Endometrial Cancer 8 5.00 Body Weight 4 5.00 Targeted Disruption 3 5.00 Breast Cancer 3 5.00 Sprains And Strains 2 5.00 Hyperplasia 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

A standard immunohistochemical technique (avidin-biotin-peroxidase) was used to visualize PCNA and Ki-67 immunostaining intensity and distribution.

Negative_regulation (visualize) of Ki-67

1) Confidence 0.10 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC156658 Disease Relevance 0 Pain Relevance 0

In all the following cases a relationship present in the BLA lesion group was notably weaker, if not absent, than in the intact BLA group: (i) a negative influence of fluoxetine in FST immobility; (ii) a positive relationship of BrdU on FST immobility; and (iii) a negative influence of anxiety in Ki67.

Negative_regulation (influence) of Ki67 associated with anxiety disorder, amygdala and fluoxetine

2) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2799663 Disease Relevance 0.47 Pain Relevance 0.71

General Comments

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