INT173756

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Context Info
Confidence 0.36
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.83
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Ghr) extracellular space (Ghr) extracellular region (Ghr)
plasma membrane (Ghr) nucleus (Ghr) cytoplasm (Ghr)
Anatomy Link Frequency
uterine 2
Ghr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 52 88.24 High High
imagery 2 44.52 Quite Low
agonist 8 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sepsis 37 98.60 Very High Very High Very High
Hyperplasia 2 93.48 High High
Endometrial Cancer 16 89.52 High High
Starvation 5 77.20 Quite High
Critical Illness 9 5.00 Very Low Very Low Very Low
Body Weight 7 5.00 Very Low Very Low Very Low
Breast Cancer 6 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Advanced Or Metastatic Breast Cancer 2 5.00 Very Low Very Low Very Low
Delayed Puberty 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nutrition increased the expression of mRNA of both IGF-I and the GHR, while these were not affected by sepsis.
Positive_regulation (increased) of Transcription (expression) of GHR associated with sepsis
1) Confidence 0.36 Published 2007 Journal Crit Care Section Body Doc Link PMC2206515 Disease Relevance 0.49 Pain Relevance 0.09
The wet weight of the uteri showed a similar pattern as induction of LE height and the GH-receptor mRNA levels, implicating that GH is involved in the regulation of uterine weight.
Positive_regulation (induction) of Transcription (levels) of GH-receptor in uterine
2) Confidence 0.19 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC156658 Disease Relevance 0.35 Pain Relevance 0
The GH-receptor mRNA level was increased in the uteri of the animals that were treated with E2 as compared to the ICI group (Fig. 1).
Positive_regulation (increased) of Transcription (level) of GH-receptor
3) Confidence 0.18 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC156658 Disease Relevance 0 Pain Relevance 0

General Comments

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