INT173977

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Context Info
Confidence 0.03
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TNF, Ighg1) signal transduction (TNF) extracellular region (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
TNF (Homo sapiens)
Ighg1 (Mus musculus)
Pain Link Frequency Relevance Heat
Infliximab 8 99.74 Very High Very High Very High
Etanercept 4 90.36 High High
cytokine 5 71.64 Quite High
Inflammation 3 58.16 Quite High
withdrawal 2 35.60 Quite Low
methotrexate 31 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 9 96.00 Very High Very High Very High
Infection 9 68.80 Quite High
Granulomatous Inflammation 2 58.16 Quite High
Microscopic Polyangiitis 12 45.52 Quite Low
Increased Venous Pressure Under Development 13 43.76 Quite Low
Disease 41 39.44 Quite Low
Fatigue 1 27.52 Quite Low
Myalgia 1 26.80 Quite Low
Rheumatoid Vasculitis 2 11.52 Low Low
Malignant Neoplastic Disease 2 6.12 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Three reports, each including less than 10 patients with WG, have utilized infliximab, a chimeric IgG1 monoclonal antibody that binds to TNF.
TNF Binding (binds) of IgG1 associated with infliximab
1) Confidence 0.03 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC165064 Disease Relevance 0.28 Pain Relevance 0.39

General Comments

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