INT174127

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Context Info
Confidence 0.45
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 4.90
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sod1) aging (Sod1) peroxisome (Sod1)
intracellular (Sod1) protein complex (Sod1) cytoplasm (Sod1)
Sod1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 15 96.28 Very High Very High Very High
Spinal cord 9 94.60 High High
Multiple sclerosis 6 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 219 98.80 Very High Very High Very High
INFLAMMATION 15 96.28 Very High Very High Very High
Targeted Disruption 13 91.60 High High
Stress 21 90.24 High High
Nerve Degeneration 8 86.60 High High
Wound Healing 87 82.56 Quite High
Keloid Scars 3 75.44 Quite High
Death 13 75.36 Quite High
Shock 1 66.88 Quite High
Apoptosis 2 62.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that mitochondrial vacuolation represents an accelerated form of mitochondrial damage caused by high levels of mutant SOD1 accumulation.
Positive_regulation (levels) of Positive_regulation (accumulation) of SOD1
1) Confidence 0.45 Published 2003 Journal BMC Neurosci Section Body Doc Link PMC169170 Disease Relevance 0.52 Pain Relevance 0.05
UA2 treatment results in increased levels of SOD1, and decreased accumulation of protein carbonyls and nitrated proteins, in the wound tissue
Positive_regulation (results) of Positive_regulation (levels) of SOD1 associated with injury
2) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2850366 Disease Relevance 1.46 Pain Relevance 0.05
UA2 treatment results in increased levels of SOD1, and decreased accumulation of protein carbonyls and nitrated proteins, in the wound tissue
Positive_regulation (increased) of Positive_regulation (levels) of SOD1 associated with injury
3) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2850366 Disease Relevance 1.45 Pain Relevance 0.05
UA2 treatment results in increased levels of SOD1, and decreased accumulation of protein carbonyls and nitrated proteins, in the wound tissue
Positive_regulation (results) of Positive_regulation (increased) of SOD1 associated with injury
4) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2850366 Disease Relevance 1.46 Pain Relevance 0.05

General Comments

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