INT174191

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Context Info
Confidence 0.02
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (LILRA3) extracellular region (LILRA3) plasma membrane (LILRA3)
LILRA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 7 50.64 Quite High
Inflammation 12 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 129 97.96 Very High Very High Very High
Ovarian Cancer 1 78.56 Quite High
Infection 2 66.96 Quite High
Breast Cancer 8 39.60 Quite Low
Metastasis 5 38.36 Quite Low
Carcinoma 2 24.56 Low Low
Toxicity 7 21.12 Low Low
Papillomavirus Infection 10 18.48 Low Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Pox Virus Infection 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another recombinant adenovirus vector in which p53-dependent expression of a fusion protein (E2F-Rb) selectively attenuated viral replication in normal cells, was further modified by insertion of the viral late promoter (MLP) in the E3 region with the aim of driving overexpression of Ad5-E3 11.6K protein, thereby increasing cytotoxicity in tumour cells, while decreasing cytotoxicity in normal cells.
Positive_regulation (overexpression) of Gene_expression (overexpression) of E3 associated with cancer
1) Confidence 0.02 Published 2003 Journal J Biomed Biotechnol Section Body Doc Link PMC179760 Disease Relevance 0.84 Pain Relevance 0.03

General Comments

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