INT174241

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Context Info
Confidence 0.65
First Reported 2003
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.00
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (ADCY5) signal transduction (ADCY5) small molecule metabolic process (ADCY5)
plasma membrane (ADCY5) GTPase activity (ADCY5) transmembrane transport (ADCY5)
Anatomy Link Frequency
AC2 1
ADCY5 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 11 78.36 Quite High
alcohol 1 73.64 Quite High
Kinase C 11 50.52 Quite High
Glutamate 5 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
Paracetamol 4 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cold Sores 36 100.00 Very High Very High Very High
Glioblastoma 4 99.72 Very High Very High Very High
Ovarian Cancer 6 91.64 High High
Chromosome Aberrations 1 76.92 Quite High
Suicidal Behaviour 7 65.12 Quite High
Death 2 58.92 Quite High
Apoptosis 5 58.68 Quite High
Reprotox - General 1 7 18.00 Low Low
Cancer 60 12.24 Low Low
Colon Cancer 16 9.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that Ishikawa cells express mRNA for AC1, AC3, AC4, AC5, AC6, AC7, AC9 and the soluble AC (SAC), but not AC2 or AC8 isoforms (data not shown).
Neg (not) Gene_expression (express) of AC5 in AC2
1) Confidence 0.65 Published 2010 Journal Cell Signal Section Body Doc Link PMC2791881 Disease Relevance 0 Pain Relevance 0.10
In other studies using U251tk human glioblastoma cells stably expressing HSV-Tk, ACV gave a lesser cell kill than did GCV (< 1.5 log compared to > 4 log) [10].
Gene_expression (expressing) of ACV associated with cold sores and glioblastoma
2) Confidence 0.26 Published 2003 Journal J Biomed Biotechnol Section Body Doc Link PMC179761 Disease Relevance 1.00 Pain Relevance 0.04

General Comments

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