INT174278

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Context Info
Confidence 0.20
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.61
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gopc) Golgi apparatus (Gopc) plasma membrane (Gopc)
cytoplasm (Gopc)
Anatomy Link Frequency
plasma 2
Gopc (Mus musculus)
Pain Link Frequency Relevance Heat
COX2 29 93.68 High High
Pain 17 84.80 Quite High
Inflammatory mediators 8 83.92 Quite High
Nerve growth factor 45 80.72 Quite High
intrathecal 10 75.04 Quite High
substance P 9 68.68 Quite High
allodynia 39 65.88 Quite High
Inflammation 15 26.64 Quite Low
Painful diabetic neuropathy 27 5.00 Very Low Very Low Very Low
Trk A 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 15 84.80 Quite High
INFLAMMATION 23 83.92 Quite High
Nociception 6 82.60 Quite High
Diabetes Mellitus 77 80.60 Quite High
Neuropathic Pain 48 65.88 Quite High
Diabetic Neuropathy 36 5.00 Very Low Very Low Very Low
Body Weight 18 5.00 Very Low Very Low Very Low
Hyperalgesia 7 5.00 Very Low Very Low Very Low
Obesity 5 5.00 Very Low Very Low Very Low
Nervous System Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SB203580 treatment significantly decreased the upregulation of all three genes (Fig. 5A-C).
Negative_regulation (decreased) of Regulation (upregulation) of Fig
1) Confidence 0.20 Published 2010 Journal Mol Pain Section Body Doc Link PMC2881061 Disease Relevance 0.40 Pain Relevance 0.53
However, preventing the elevation of corticosterone completely blocked the effect of fasting on hypothalamic AGRP and POMC mRNA (Fig. 2A and 2B), without preventing effects of fasting on plasma leptin or insulin.
Negative_regulation (blocked) of Regulation (effect) of Fig in plasma
2) Confidence 0.20 Published 2003 Journal BMC Physiol Section Body Doc Link PMC179893 Disease Relevance 0.22 Pain Relevance 0

General Comments

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