INT174280

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Context Info
Confidence 0.40
First Reported 2003
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.20
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Npy) extracellular region (Npy)
Npy (Mus musculus)
Pain Link Frequency Relevance Heat
Intracerebroventricular 10 93.12 High High
Hippocampus 3 36.96 Quite Low
dexamethasone 8 5.00 Very Low Very Low Very Low
Eae 8 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Neuropeptide 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 67 99.64 Very High Very High Very High
Body Weight 64 89.68 High High
Metabolic Syndrome 4 77.60 Quite High
Obesity 35 65.08 Quite High
Sprains And Strains 3 53.44 Quite High
Stress 1 49.36 Quite Low
Hyperphagia 3 49.00 Quite Low
Congenital Anomalies 1 44.24 Quite Low
Insulin Resistance 5 5.00 Very Low Very Low Very Low
Hyperinsulinism 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the finding of attenuated induction of Npy and Agrp mRNAs in the hypothalami of fasted CXCL14?
Negative_regulation (attenuated) of Positive_regulation (induction) of Npy
1) Confidence 0.40 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2859050 Disease Relevance 0.17 Pain Relevance 0.05
As with AGRP mRNA, NPY mRNA was elevated in diabetic mice, and adrenalectomy blocked this induction of NPY mRNA in diabetic mice whether or not they were fasted (Fig. 4C).
Spec (whether) Negative_regulation (blocked) of Spec (whether) Positive_regulation (induction) of NPY associated with diabetes mellitus
2) Confidence 0.31 Published 2003 Journal BMC Physiol Section Body Doc Link PMC179893 Disease Relevance 0.64 Pain Relevance 0
Adrenalectomy has been reported to block elevations in NPY mRNA in response to fasting [14].
Negative_regulation (block) of Positive_regulation (elevations) of NPY
3) Confidence 0.31 Published 2003 Journal BMC Physiol Section Body Doc Link PMC179893 Disease Relevance 0.40 Pain Relevance 0

General Comments

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