INT174311

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Context Info
Confidence 0.04
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Rap1a) signal transduction (Rap1a) plasma membrane (Rap1a)
cytoskeleton (Krit1) GTPase activity (Rap1a) protein complex (Krit1)
Anatomy Link Frequency
terminal portion 1
Krit1 (Mus musculus)
Rap1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cva 10 69.80 Quite High
headache 4 68.40 Quite High
imagery 2 60.16 Quite High
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemangioma 2 86.64 High High
Cavernous Hemangioma 4 78.68 Quite High
Cv General 3 Under Development 10 69.80 Quite High
Convulsion 2 68.80 Quite High
Headache 4 68.40 Quite High
Epilepsy 4 67.96 Quite High
Disease 2 58.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
KRIT1 encodes a 736 amino-acids protein containing four ankyrin domains, a FERM domain and a C-terminal portion that interacts with Rap1A.
KRIT1 Binding (interacts) of Rap1A in terminal portion
1) Confidence 0.04 Published 2003 Journal BMC Neurol Section Body Doc Link PMC184376 Disease Relevance 0.58 Pain Relevance 0.14
The Krit1 protein was identified by its interaction with Rap1A, a small Ras like GTPase [7].
Krit1 Binding (interaction) of Rap1A
2) Confidence 0.04 Published 2003 Journal BMC Neurol Section Body Doc Link PMC184376 Disease Relevance 0.49 Pain Relevance 0.13

General Comments

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