INT174348

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Context Info
Confidence 0.23
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 0.30
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Vmn1r51) plasma membrane (Vmn1r51) signal transducer activity (Vmn1r51)
Anatomy Link Frequency
vomeronasal organ 1
arcuate nucleus 1
neurons 1
epithelium 1
olfactory epithelium 1
Vmn1r51 (Mus musculus)
Pain Link Frequency Relevance Heat
sodium channel 3 82.28 Quite High
HCN1 3 76.44 Quite High
Neuropeptide 3 75.24 Quite High
Somatostatin 11 73.24 Quite High
imagery 3 48.96 Quite Low
Action potential 22 5.00 Very Low Very Low Very Low
antagonist 13 5.00 Very Low Very Low Very Low
Glutamate 13 5.00 Very Low Very Low Very Low
cytokine 12 5.00 Very Low Very Low Very Low
Calcium channel 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 21 82.72 Quite High
Aggression 6 73.60 Quite High
Sprains And Strains 15 5.00 Very Low Very Low Very Low
Poisoning 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Ganglion Cysts 3 5.00 Very Low Very Low Very Low
Decapitation 3 5.00 Very Low Very Low Very Low
Helminth Infection 2 5.00 Very Low Very Low Very Low
Alopecia 2 5.00 Very Low Very Low Very Low
Paralysis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The apically expressed V1R family has 135 members in the mouse, which have from 25% to nearly 100% amino-acid sequence identity to each other, and their genes are organized in several gene clusters [37].
Gene_expression (expressed) of V1R
1) Confidence 0.23 Published 2003 Journal Genome Biol Section Body Doc Link PMC193622 Disease Relevance 0 Pain Relevance 0.07
It is therefore not clear whether the few human V1R sequences that have been identified are expressed as functional receptors, in tissues, such as the main olfactory epithelium.
Gene_expression (expressed) of V1R in olfactory epithelium
2) Confidence 0.20 Published 2003 Journal Genome Biol Section Body Doc Link PMC193622 Disease Relevance 0.30 Pain Relevance 0
The sensory epithelium of the vomeronasal organ is arranged in a basal and apical layer, each of which expresses one type of pheromone receptor belonging to either the V1R or the V2R family of GPCRs (Figure 1a and Table 1) [11,35].
Gene_expression (expresses) of V1R in vomeronasal organ
3) Confidence 0.20 Published 2003 Journal Genome Biol Section Body Doc Link PMC193622 Disease Relevance 0 Pain Relevance 0.08
Vomeronasal receptor neurons express receptors from two main multigene families, V1R and V2R receptors, [27-30].
Gene_expression (express) of V1R in neurons
4) Confidence 0.09 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1550415 Disease Relevance 0 Pain Relevance 0
, each of which are confined to the superficial and deep layers of the vomeronasal epithelium respectively, and appear to be co-expressed with the V1R and V2R family of receptors, respectively [31-34].
Gene_expression (expressed) of V1R in epithelium
5) Confidence 0.08 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1550415 Disease Relevance 0 Pain Relevance 0
The ghrelin receptor (GHSR, growth hormone secretagogue receptor-1) is found in several neuronal subtypes in the arcuate nucleus [8]–[11], where a diffuse pattern of ghrelin-containing terminals has been demonstrated [12].
Gene_expression (found) of receptor-1 in arcuate nucleus
6) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2820089 Disease Relevance 0 Pain Relevance 0.07

General Comments

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