INT174416

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Context Info
Confidence 0.33
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.06
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cxcr2) plasma membrane (Cxcr2) intracellular (Cxcr2)
signal transducer activity (Cxcr2)
Anatomy Link Frequency
skin 2
Cxcr2 (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 50 99.88 Very High Very High Very High
rheumatoid arthritis 102 98.20 Very High Very High Very High
Inflammation 124 92.92 High High
chemokine 49 90.48 High High
cytokine 33 5.00 Very Low Very Low Very Low
metalloproteinase 20 5.00 Very Low Very Low Very Low
antagonist 19 5.00 Very Low Very Low Very Low
Bioavailability 11 5.00 Very Low Very Low Very Low
Arthritis 9 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 50 99.88 Very High Very High Very High
Injury 8 98.68 Very High Very High Very High
Rheumatoid Arthritis 107 98.20 Very High Very High Very High
INFLAMMATION 130 92.92 High High
Disease 26 91.80 High High
Pulmonary Disease 144 60.24 Quite High
Adhesions 9 30.40 Quite Low
Stress 23 16.32 Low Low
Nicotine Addiction 49 5.00 Very Low Very Low Very Low
Emphysema 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Distribution and cellular assignment of CXCR1, CXCR2, and CXCR3 to different cellular subsets in RA and OA tissues
Negative_regulation (assignment) of Gene_expression (Distribution) of CXCR2 associated with rheumatoid arthritis and osteoarthritis
1) Confidence 0.33 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193722 Disease Relevance 1.37 Pain Relevance 0.61
In vivo, impaired CXCR2 expression in mice resulted in delayed skin wound repair as compared to wild type mice, which cannot be restored by exogenous CXCL8 (Devalaraja et al 2000; Milatovic et al 2003).
Negative_regulation (impaired) of Gene_expression (expression) of CXCR2 in skin associated with injury
2) Confidence 0.27 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2695202 Disease Relevance 0.70 Pain Relevance 0.21

General Comments

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