INT174425

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.48
First Reported 2003
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.05
Pain Relevance 1.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cxcr3) plasma membrane (Cxcr3) signal transducer activity (Cxcr3)
Cxcr3 (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 100 98.68 Very High Very High Very High
rheumatoid arthritis 204 98.28 Very High Very High Very High
chemokine 60 96.40 Very High Very High Very High
Inflammation 59 83.60 Quite High
Multiple sclerosis 1 79.80 Quite High
cytokine 17 71.32 Quite High
psoriasis 2 56.00 Quite High
Central nervous system 1 50.40 Quite High
Arthritis 14 38.32 Quite Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 100 98.68 Very High Very High Very High
Rheumatoid Arthritis 204 98.28 Very High Very High Very High
INFLAMMATION 69 83.60 Quite High
Demyelinating Disease 1 79.80 Quite High
Multiple Sclerosis 1 78.68 Quite High
Shock 1 74.40 Quite High
Hyperplasia 6 70.48 Quite High
Psoriasis 4 56.00 Quite High
Arthritis 16 38.32 Quite Low
Chronic Disease 4 35.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data indicate that increasing CXCR3 protein levels are most likely due to enhanced recruitment of MCs that express CXCR3 in RA synovial tissue.
Positive_regulation (due) of Positive_regulation (increasing) of CXCR3 protein associated with rheumatoid arthritis
1) Confidence 0.48 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193722 Disease Relevance 1.41 Pain Relevance 0.77
Significantly increased levels of CXCR1, CXCR2, and CXCR3 mRNA, as well as highly abundant CXCR1 and CXCR3 protein levels, were found in synovial tissue from RA as compared with that from OA patients.
Positive_regulation (increased) of Positive_regulation (levels) of CXCR3 associated with rheumatoid arthritis and osteoarthritis
2) Confidence 0.44 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193722 Disease Relevance 1.33 Pain Relevance 0.75
TEPM expressed elevated levels of mRNA for Cxcr4, Ccr1, Ccrl2, whilst BMM expressed higher levels of Ccr2, Cx3cr1 and Cxcr3.
Positive_regulation (elevated) of Positive_regulation (levels) of Cxcr3
3) Confidence 0.40 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.32 Pain Relevance 0.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox