INT174438

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Context Info
Confidence 0.66
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.58
Pain Relevance 2.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cxcr3) plasma membrane (Cxcr3) signal transducer activity (Cxcr3)
Cxcr3 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 306 99.36 Very High Very High Very High
Osteoarthritis 150 98.56 Very High Very High Very High
chemokine 87 98.16 Very High Very High Very High
Inflammation 72 65.12 Quite High
cytokine 24 5.00 Very Low Very Low Very Low
Arthritis 21 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 306 99.36 Very High Very High Very High
Osteoarthritis 150 98.56 Very High Very High Very High
INFLAMMATION 72 65.12 Quite High
Disease 39 58.68 Quite High
Arthritis 24 5.00 Very Low Very Low Very Low
Adhesions 12 5.00 Very Low Very Low Very Low
Hyperplasia 9 5.00 Very Low Very Low Very Low
Necrosis 9 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Psoriasis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased CXCR3 mRNA expression within synovial tissue from RA versus OA patients is reflected by higher CXCR3/TCR-?
Positive_regulation (Increased) of Transcription (expression) of CXCR3 associated with rheumatoid arthritis and osteoarthritis
1) Confidence 0.66 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193722 Disease Relevance 1.88 Pain Relevance 1.01
This an increase of 3.6-fold in CXCR3 transcript levels was found in synovial tissue of RA patients (Fig. 2a,2b).
Positive_regulation (increase) of Transcription (levels) of CXCR3 associated with rheumatoid arthritis
2) Confidence 0.44 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193722 Disease Relevance 1.33 Pain Relevance 0.80
RT-PCR revealed increased CXCR3 mRNA levels (P < 0.001) in RA as compared with OA synovial tissue (Fig. 2a).
Positive_regulation (increased) of Transcription (levels) of CXCR3 associated with rheumatoid arthritis and osteoarthritis
3) Confidence 0.44 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193722 Disease Relevance 1.37 Pain Relevance 0.82

General Comments

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