INT174500

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Context Info
Confidence 0.21
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.33
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD4, HLA-B) signal transduction (CD4) cell adhesion (CD4)
enzyme binding (CD4)
CD4 (Homo sapiens)
HLA-B (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 100 81.60 Quite High
Inflammation 8 58.68 Quite High
rheumatoid arthritis 12 40.72 Quite Low
spondylitis 8 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 14 85.00 Quite High
Low Back Pain 108 81.60 Quite High
Cytomegalovirus Infection 26 80.96 Quite High
Spondylarthropathies 2 79.60 Quite High
Epstein-barr Virus 24 79.16 Quite High
Disease 56 63.40 Quite High
INFLAMMATION 8 58.68 Quite High
Apoptosis 14 56.56 Quite High
Skin Cancer 2 25.36 Quite Low
Demyelinating Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Most of the HLA-B27 mediated proliferative effect could be inhibited by CD4 specific monoclonal antibodies, suggesting a CD4 mediated recognition of the HLA-B27 molecule.
Positive_regulation (mediated) of CD4 Binding (recognition) of HLA-B27
1) Confidence 0.21 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193730 Disease Relevance 1.10 Pain Relevance 0.30
Most of the HLA-B27 mediated proliferative effect could be inhibited by CD4 specific monoclonal antibodies, suggesting a CD4 mediated recognition of the HLA-B27 molecule.
Positive_regulation (mediated) of CD4 Binding (recognition) of HLA-B27
2) Confidence 0.15 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193730 Disease Relevance 1.23 Pain Relevance 0.33

General Comments

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