INT174501

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Context Info
Confidence 0.03
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.84
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HLA-B, HLA-DOA) endosome (HLA-DOA)
HLA-B (Homo sapiens)
HLA-DOA (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 58 100.00 Very High Very High Very High
Multiple sclerosis 14 99.68 Very High Very High Very High
rheumatoid arthritis 13 65.60 Quite High
Arthritis 2 40.64 Quite Low
Inflammation 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
spondylitis 4 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Low Back Pain 62 100.00 Very High Very High Very High
Diabetes Mellitus 17 100.00 Very High Very High Very High
Demyelinating Disease 14 99.68 Very High Very High Very High
Disease 51 99.00 Very High Very High Very High
Graves' Ophthalmopathy 3 98.76 Very High Very High Very High
Autoimmune Disease 47 90.84 High High
Viral Infection 2 90.16 High High
Rheumatoid Arthritis 14 65.60 Quite High
Targeted Disruption 2 52.72 Quite High
Arthritis 1 40.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Association of the HLA class I region, independent of known HLA class II effects, has now been detected for several AIDs, including strong association of HLA-B with type 1 diabetes and HLA-C with multiple sclerosis and Graves’ disease.
HLA-B Binding (association) of HLA associated with multiple sclerosis, diabetes mellitus, graves' ophthalmopathy and disease
1) Confidence 0.03 Published 2007 Journal Current Genomics Section Abstract Doc Link PMC2647156 Disease Relevance 1.43 Pain Relevance 0.16
The immunogenetic link between HLA-B27 and ankylosing spondylitis (AS) is the strongest reported association of an HLA class I molecule with a disease to date.
HLA-B27 Binding (association) of HLA associated with spinal inflammation and disease
2) Confidence 0.00 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193730 Disease Relevance 0.41 Pain Relevance 0.26

General Comments

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