INT174530

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Context Info
Confidence 0.16
First Reported 2003
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.42
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD7)
Anatomy Link Frequency
bone marrow 2
T cells 2
CD7 (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 50 98.36 Very High Very High Very High
rheumatoid arthritis 6 89.52 High High
Inflammation 5 31.72 Quite Low
tolerance 1 30.88 Quite Low
Pain 1 29.08 Quite Low
cytokine 8 18.04 Low Low
spondylitis 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Low Back Pain 54 98.36 Very High Very High Very High
Rheumatoid Arthritis 7 89.52 High High
Spondylarthropathies 1 87.56 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 5 86.44 High High
Disease 30 85.28 High High
Adult T-cell Leukemia-lymphoma 11 82.80 Quite High
Skin Cancer 1 74.16 Quite High
Hypercalcemia 29 65.84 Quite High
Osteoporosis 2 58.24 Quite High
Cytomegalovirus Infection 13 54.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, the CD4+CD28- T cells from AS patients that we tested expressed high levels of CD57 and NK receptors, but they lacked expression of CD7, thus sharing typical NK cell features [39].
Negative_regulation (lacked) of Neg (lacked) Gene_expression (expression) of CD7 in T cells associated with spinal inflammation
1) Confidence 0.16 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193730 Disease Relevance 1.05 Pain Relevance 0.48
Flow cytometry of the bone marrow biopsy revealed that the majority of cells were immunoreactive for CD45, CD2, CD3, CD4, and CD30, whereas the expression of CD5 and CD7 was greatly reduced compared to CD2 and CD3.
Negative_regulation (reduced) of Gene_expression (expression) of CD7 in bone marrow
2) Confidence 0.15 Published 2007 Journal J Gen Intern Med Section Body Doc Link PMC1824742 Disease Relevance 0.37 Pain Relevance 0

General Comments

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