INT174554

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Context Info
Confidence 0.20
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.53
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T cells 4
Cd8a (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 3 65.60 Quite High
Inflammation 23 65.20 Quite High
Neuropeptide 4 50.00 Quite Low
Arthritis 4 50.00 Quite Low
rheumatoid arthritis 45 11.44 Low Low
tolerance 9 9.60 Low Low
melanocortin 1 receptor 5 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 16 100.00 Very High Very High Very High
Necrosis 2 99.72 Very High Very High Very High
Cancer 48 99.54 Very High Very High Very High
Aging 12 98.94 Very High Very High Very High
Death 4 91.40 High High
Apoptosis 14 90.96 High High
INFLAMMATION 26 65.20 Quite High
Pressure And Volume Under Development 3 58.20 Quite High
Autoimmune Disease 9 50.00 Quite Low
Arthritis 2 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-MSH to MC-1R was required for the reduction of contact allergy CD8+ T cells from C57BL/6Je/e mice were stimulated with ?
Positive_regulation (stimulated) of Negative_regulation (reduction) of CD8 in T cells associated with hypersensitivity
1) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2813861 Disease Relevance 0.99 Pain Relevance 0
Replicative senescence and chronic exposure to tumor necrosis factor alpha induce a loss of this initiator complex, particularly in CD8+ T cells [51].
Positive_regulation (induce) of Negative_regulation (loss) of CD8 in T cells associated with necrosis, aging and cancer
2) Confidence 0.05 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193735 Disease Relevance 0.54 Pain Relevance 0.07

General Comments

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