INT174652

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Context Info
Confidence 0.05
First Reported 2003
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.49
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (EXTL3)
EXTL3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dysuria 1 61.16 Quite High
Calcium channel 1 58.80 Quite High
Angina 2 54.88 Quite High
Inflammation 18 50.00 Quite Low
agonist 1 40.96 Quite Low
Bioavailability 2 18.20 Low Low
abdominal pain 1 14.48 Low Low
fibrosis 3 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Lupus Erythematosus 1 100.00 Very High Very High Very High
Diabetes Mellitus 23 99.84 Very High Very High Very High
Targeted Disruption 4 99.48 Very High Very High Very High
Hepatitis A Virus Infection 1 97.56 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 96.56 Very High Very High Very High
Proteinuria 7 82.84 Quite High
Nephrosis 1 77.40 Quite High
Disorder Of Lipid Metabolism 16 70.72 Quite High
Sclerosis 1 64.48 Quite High
Hematuria 2 62.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, tests for ANA, RPR, rheumatoid factor, c-ANCA, p-ANCA, cryoglobulin, lupus anticoagulant and anticardiolipin antibodies were negative.
Neg (negative) Gene_expression (negative) of RPR associated with systemic lupus erythematosus
1) Confidence 0.05 Published 2003 Journal BMC Nephrol Section Body Doc Link PMC194618 Disease Relevance 1.29 Pain Relevance 0.12
Although the drug does not block direct intracellular effects, Feldman et al reported that aliskiren downregulates RPR expression in diabetic transgenic rats.14 In humans we have no direct evidence of this.
Gene_expression (expression) of RPR associated with targeted disruption and diabetes mellitus
2) Confidence 0.05 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2952455 Disease Relevance 0.20 Pain Relevance 0.03

General Comments

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