INT174663

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Context Info
Confidence 0.11
First Reported 2003
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.45
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (KAT8) transcription factor binding (KAT8)
KAT8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 17 99.88 Very High Very High Very High
cytokine 22 96.44 Very High Very High Very High
cva 49 66.44 Quite High
Inflammatory response 10 56.24 Quite High
Inflammatory mediators 3 30.32 Quite Low
potassium channel 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
tissue acidosis 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Organ Failure 69 100.00 Very High Very High Very High
Sepsis 45 99.98 Very High Very High Very High
INFLAMMATION 27 99.88 Very High Very High Very High
Injury 106 99.68 Very High Very High Very High
Cv General 2 Under Development 17 99.14 Very High Very High Very High
Hemorrhagic Shock 46 93.68 High High
Death 20 90.44 High High
Apoptosis 1 90.00 High High
Emergencies 9 73.00 Quite High
Disease 6 70.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although the aim of trauma research is to detect MOF as early as possible, this time protocol seems to be representative for current studies.
Spec (possible) Positive_regulation (detect) of MOF associated with multiple organ failure and injury
1) Confidence 0.11 Published 2008 Journal Crit Care Section Body Doc Link PMC2592747 Disease Relevance 1.31 Pain Relevance 0.08
What is striking about our findings is the importance of the first delay, which itself is made up of a series of significant delays.
Positive_regulation (importance) of first delay
2) Confidence 0.07 Published 2003 Journal BMC Int Health Hum Rights Section Body Doc Link PMC194728 Disease Relevance 0.13 Pain Relevance 0
It is well known that shock initiates dysfunctional inflammation that causes MOF.
Positive_regulation (causes) of MOF associated with multiple organ failure, inflammation and cv general 2 under development
3) Confidence 0.07 Published 2008 Journal Crit Care Section Body Doc Link PMC2575549 Disease Relevance 0.92 Pain Relevance 0.11
Sepsis-induced MOF may thus be related to a potentially reversible impairment in cellular function rather than any permanent structural damage.
Positive_regulation (induced) of MOF associated with multiple organ failure and sepsis
4) Confidence 0.06 Published 2006 Journal Crit Care Section Body Doc Link PMC1751057 Disease Relevance 1.09 Pain Relevance 0.03

General Comments

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