INT174850

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Context Info
Confidence 0.33
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 0.51
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ISCU) mitochondrion (ISCU) nucleus (ISCU)
cytoplasm (ISCU)
ISCU (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 9 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Muscle Disease 36 80.96 Quite High
Hypoxia 8 80.80 Quite High
Shock 2 80.08 Quite High
Iron Overload 96 71.60 Quite High
Disease 108 50.00 Quite Low
Hyperplasia 4 48.92 Quite Low
Neurologic Manifestations 4 43.16 Quite Low
Ataxia 96 41.08 Quite Low
Smear Layer 1 41.00 Quite Low
Cirrhosis 4 40.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Isu1, its homologue Isu2, Nfu, Isa1, and Isa2 are all proposed to function as scaffold proteins upon which Fe?
Isu2 Binding (function) of
1) Confidence 0.33 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0 Pain Relevance 0
Importantly, the cytosolic isoform of ISCU has been shown to have a role similar to that of its mitochondrial counterpart in Fe?
ISCU Binding (counterpart) of
2) Confidence 0.33 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.16 Pain Relevance 0
Isu1, its homologue Isu2, Nfu, Isa1, and Isa2 are all proposed to function as scaffold proteins upon which Fe?
Isu2 Binding (homologue) of
3) Confidence 0.33 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0 Pain Relevance 0
Silencing of c-ISCU by siRNA impairs Fe?
c-ISCU Binding (Silencing) of
4) Confidence 0.29 Published 2010 Journal Biochemistry Section Body Doc Link PMC2885827 Disease Relevance 0.28 Pain Relevance 0
As a further additive glutaric aldehyde can be helpful with protein fixation of collagen fibers.
fixation Binding (helpful) of
5) Confidence 0.02 Published 2003 Journal Biomed Eng Online Section Body Doc Link PMC222922 Disease Relevance 0.08 Pain Relevance 0

General Comments

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