INT174875

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Context Info
Confidence 0.43
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.56
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
heart 2
muscle 1
Myl3 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 28 79.48 Quite High
Angina 1 62.20 Quite High
addiction 2 50.00 Quite Low
agonist 6 36.72 Quite Low
Inflammation 12 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 18 97.92 Very High Very High Very High
Shock 152 97.84 Very High Very High Very High
Metastasis 4 95.64 Very High Very High Very High
Superior Vena Cava Syndrome 1 95.08 Very High Very High Very High
Cv Unclassified Under Development 33 93.92 High High
Lymphadenopathy 1 93.80 High High
Pericardial Effusion 11 91.64 High High
Emergencies 1 85.28 High High
Stress 25 81.64 Quite High
Heart Rate Under Development 2 80.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SRF plays a prominent role in regulating the expression of heart muscle genes [33] and may explain increases in muscle contraction genes (ACTA1, ACTA2, DES, MYL1, MYL2, MYL3, MYL9, MYOM1, TNNC2, TNNT1, TNNT3, TPM2, TPM4) after HS.
Gene_expression (expression) of MYL3 in muscle associated with shock
1) Confidence 0.43 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 0.75 Pain Relevance 0
Diagnostic right heart catheterization revealed a central venous pressure of 21 cm H2O, a right ventricular pressure of 40/21 mm Hg and a pulmonary artery pressure of 22 mm Hg.
Gene_expression (pressure) of ventricular in heart
2) Confidence 0.07 Published 2003 Journal World J Surg Oncol Section Body Doc Link PMC239964 Disease Relevance 1.35 Pain Relevance 0.06
The hemodynamic parameters{mean arterial pressure (MAP), heart rate (HR), left ventricular end-diastolic pressure (LVEDP), left ventricular peak positive (+) LVdP/dt (rate of pressure development) and negative (-) LVdP/dt (rate of pressure decline)} were monitored at pre-set points throughout the experimental duration and subsequently, the animals were sacrificed for immunohistopathological (Bax, Bcl-2 protein expression & TUNEL positivity) and histopathological studies.


Gene_expression (expression) of ventricular in heart
3) Confidence 0.01 Published 2006 Journal BMC Complement Altern Med Section Abstract Doc Link PMC1397864 Disease Relevance 0.46 Pain Relevance 0.04

General Comments

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