INT174876

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Context Info
Confidence 0.39
First Reported 2003
Last Reported 2010
Negated 5
Speculated 1
Reported most in Body
Documents 18
Total Number 19
Disease Relevance 7.83
Pain Relevance 2.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Fig4) Golgi apparatus (Fig4) endoplasmic reticulum (Fig4)
Anatomy Link Frequency
lung 4
plasma 2
hepatocytes 2
liver 2
muscles 2
Fig4 (Rattus norvegicus)
Fig4 - C113Y (1)
Pain Link Frequency Relevance Heat
dorsal root ganglion 71 100.00 Very High Very High Very High
Inflammatory response 15 99.82 Very High Very High Very High
nMDA receptor 10 98.72 Very High Very High Very High
Demyelination 47 98.08 Very High Very High Very High
Pyramidal cell 28 98.08 Very High Very High Very High
Inflammation 142 95.80 Very High Very High Very High
Action potential 7 93.32 High High
Glutamate 99 91.20 High High
Glutamate receptor 18 89.96 High High
Bile 61 89.80 High High
Disease Link Frequency Relevance Heat
Respiratory Syncytial Virus 116 100.00 Very High Very High Very High
Hypersensitivity 91 100.00 Very High Very High Very High
Ganglion Cysts 79 100.00 Very High Very High Very High
Injury 56 100.00 Very High Very High Very High
Ocular Hypertension 94 99.82 Very High Very High Very High
INFLAMMATION 149 99.64 Very High Very High Very High
Nervous System Injury 32 99.64 Very High Very High Very High
Fibromyalgia 6 98.28 Very High Very High Very High
Demyelinating Disease 48 98.08 Very High Very High Very High
Infection 9 93.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The lightpipe, shown in Fig. 6a
Regulation (lightpipe) of Gene_expression (shown) of Fig
1) Confidence 0.39 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3000694 Disease Relevance 0 Pain Relevance 0
We found that in P20 animals (Fig. 3A), the peak anoxic depolarization current was not altered compared to the P12 condition (P20: 3941?
Neg (not) Regulation (altered) of Gene_expression (animals) of Fig
2) Confidence 0.25 Published 2010 Journal Brain Section Body Doc Link PMC2995884 Disease Relevance 0.09 Pain Relevance 0.03
Pyramidal neurons from acutely stressed rats displayed a significant increase in sEPSC amplitude with respect to control neurons (Fig. 5B,C), in the absence of significant effects on sEPSC frequency (D?
Regulation (control) of Gene_expression (neurons) of Fig in neurons associated with pyramidal cell
3) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2797327 Disease Relevance 0.48 Pain Relevance 0.38
0.040) without affecting 5-HTT protein expression (Fig. 5A and B).


Neg (without) Regulation (affecting) of Gene_expression (expression) of Fig
4) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2808335 Disease Relevance 0.09 Pain Relevance 0.07
The addition of TCA or insulin to primary hepatocytes resulted in the rapid phosphorylation of FOX01, a key transcription factor controlling PEPCK and G-6-Pase gene expression (Fig. 4).
Regulation (controlling) of Gene_expression (expression) of Fig in hepatocytes
5) Confidence 0.14 Published 2010 Journal Journal of Lipid Research Section Body Doc Link PMC2903791 Disease Relevance 0.31 Pain Relevance 0.21
The pattern of neuronal expression of CXCR3 mRNA at POD14 following focal nerve demyelination did not change relative to naïve or sham-treated tissue, but the nerve injury did increase the intensity of CXCR3 mRNA expression in the DRG ipsilateral to the injury (Fig. 5C), as well as in the contralateral DRG (data not shown).
Regulation (intensity) of Gene_expression (expression) of Fig in nerve associated with demyelination, nervous system injury and injury
6) Confidence 0.14 Published 2007 Journal Mol Pain Section Body Doc Link PMC2228278 Disease Relevance 0.63 Pain Relevance 0.33
Thus, based on measured basal ATP levels in control DRG (Fig. 2A) we would expect true ATP concentration at the neuronal plasma membrane to be >10 nM.
Regulation (based) of Gene_expression (levels) of Fig in plasma associated with dorsal root ganglion
7) Confidence 0.14 Published 2008 Journal Mol Pain Section Body Doc Link PMC2630978 Disease Relevance 1.32 Pain Relevance 0.47
Steady currents measured near the ends of the pulses in each condition are plotted against voltage for WT (Fig. 2 G), RD (Fig. 2 C), and C113Y (Fig. 2 E) Na/K pumps.
Regulation (voltage) of Gene_expression (pumps) of Fig (C113Y)
8) Confidence 0.12 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2894553 Disease Relevance 0 Pain Relevance 0
In contrast, progesterone treatment did not exert effects on the E-selectin expression of lung of OVX-allergic rats (Fig. 10A).
Neg (not) Regulation (effects) of Gene_expression (expression) of Fig in lung associated with hypersensitivity
9) Confidence 0.12 Published 2010 Journal Respir Res Section Body Doc Link PMC2936382 Disease Relevance 1.06 Pain Relevance 0
Here, we present the dynamic picture of steroid modulation of expression of the “greater urea cycle” (Fig. 1).


Regulation (modulation) of Gene_expression (expression) of Fig
10) Confidence 0.11 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733100 Disease Relevance 0.06 Pain Relevance 0.07
The elevated IOP was not altered by intravitreous injection of MIF or PBS (Fig. 5a).
Neg (not) Regulation (altered) of Gene_expression (injection) of Fig associated with ocular hypertension
11) Confidence 0.11 Published 2009 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2723674 Disease Relevance 1.44 Pain Relevance 0
BW-B 70C treatment reduced the IR injury-induced inflammatory response by down-regulating iNOS expression (Fig. 3A iii) via inhibition of iNOS gene expression (Fig. 3B).
Regulation (regulating) of Gene_expression (expression) of Fig associated with inflammatory response and injury
12) Confidence 0.10 Published 2006 Journal J Neuroinflammation Section Body Doc Link PMC1526713 Disease Relevance 0.55 Pain Relevance 0.10
Our data confirmed that expression of ICAM-1 in the liver was up-regulated as a result of hepatic I/Ri (Fig. 3A and 3B, p < 0.001).
Regulation (regulated) of Gene_expression (result) of Fig in liver
13) Confidence 0.09 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2873601 Disease Relevance 0.46 Pain Relevance 0.10
Interestingly, the “100 nsec” MB structure in Fig. 4B did not predict any ?
Regulation (nsec) of Gene_expression (structure) of Fig
14) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2805716 Disease Relevance 0 Pain Relevance 0
B was observed in the untreated control (Fig. 4Bi), and nuclear translocation was induced by IL-1?
Regulation (control) of Gene_expression (4Bi) of Fig
15) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2667254 Disease Relevance 0.32 Pain Relevance 0
The lungs from the NHP showed both type I and type II cells positive for GFP expression (Fig. 4, Panel A).
Regulation (positive) of Gene_expression (expression) of Fig in lungs
16) Confidence 0.05 Published 2003 Journal BMC Biotechnol Section Body Doc Link PMC239997 Disease Relevance 0.09 Pain Relevance 0
mol/L) had no effect on the picrotoxin-enhanced M1 mACh receptor desensitization (Fig. 2b; Table 1).
Neg (no) Regulation (effect) of Gene_expression (desensitization) of Fig
17) Confidence 0.05 Published 2007 Journal Journal of Neurochemistry Section Body Doc Link PMC2658029 Disease Relevance 0 Pain Relevance 0.53
M (Fig. 3).Fig3Effect of RSV analogues on the expression of myeloid markers.
Regulation (3Effect) of Gene_expression (expression) of Fig associated with respiratory syncytial virus
18) Confidence 0.05 Published 2010 Journal Calcif Tissue Int Section Body Doc Link PMC2964465 Disease Relevance 0.63 Pain Relevance 0
Electrophoretic examination of the quadriceps muscles at 21 days post surgery was performed to examine changes in the MHC expression profile (Fig. 2).
Spec (examine) Regulation (changes) of Gene_expression (expression) of Fig in muscles
19) Confidence 0.02 Published 2010 Journal Osteoarthritis and Cartilage Section Body Doc Link PMC2849930 Disease Relevance 0.28 Pain Relevance 0.15

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