INT175024

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Context Info
Confidence 0.10
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NR3C1) nucleoplasm (NR3C1) signal transduction (NR3C1)
aging (NR3C1) nucleolus (NR3C1) nucleus (NR3C1)
NR3C1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 4 99.96 Very High Very High Very High
dexamethasone 3 99.64 Very High Very High Very High
depression 28 99.10 Very High Very High Very High
antagonist 4 57.04 Quite High
fluoxetine 1 5.00 Very Low Very Low Very Low
antidepressant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 29 99.10 Very High Very High Very High
Cushing's Syndrome /

Hypercortisolism

6 5.00 Very Low Very Low Very Low
Hyperaldosteronism 4 5.00 Very Low Very Low Very Low
Depressive Disorder 2 5.00 Very Low Very Low Very Low
Affective Disorder 2 5.00 Very Low Very Low Very Low
Sleep Disorders 1 5.00 Very Low Very Low Very Low
Weight Loss 1 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Obesity 1 5.00 Very Low Very Low Very Low
Cardiovascular Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A possible link between possible changes of the RAAS and the HPA system in depression was further demonstrated by the significant increase in aldosterone secretion after administration of the glucocorticoid receptor agonist dexamethasone in healthy female subjects, whereas in depressed females aldosterone showed a trend to a decrease [32].
Positive_regulation (increase) of Localization (secretion) of glucocorticoid receptor associated with depression, agonist and dexamethasone
1) Confidence 0.10 Published 2003 Journal BMC Psychiatry Section Body Doc Link PMC280657 Disease Relevance 0.50 Pain Relevance 0.41

General Comments

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