INT175068

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Context Info
Confidence 0.19
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Ezr) cytoplasm (Ezr) cytosol (Ezr)
cytoskeletal protein binding (Ezr) structural molecule activity (Ezr) nucleolus (Ezr)
Anatomy Link Frequency
Schwann cells 1
Ezr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
sodium channel 18 99.28 Very High Very High Very High
Sciatic nerve 54 93.92 High High
Peripheral nervous system 3 57.96 Quite High
Central nervous system 6 5.00 Very Low Very Low Very Low
Nav1.6 3 5.00 Very Low Very Low Very Low
Nav1.2 3 5.00 Very Low Very Low Very Low
Action potential 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 24 38.96 Quite Low
Neuroblastoma 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both S3 and S4 were found concentrated in Schwann cells perinodal processes, co-localized with ezrin, surrounding the sodium channel clusters.
Localization (localized) of ezrin in Schwann cells associated with sodium channel
1) Confidence 0.19 Published 2003 Journal BMC Neurosci Section Body Doc Link PMC293377 Disease Relevance 0 Pain Relevance 0.23
Co-immunostaining revealed a complete colocalization of ezrin and S3 (Fig. 4B) or S4 (Fig. 4C).
Localization (colocalization) of ezrin
2) Confidence 0.18 Published 2003 Journal BMC Neurosci Section Body Doc Link PMC293377 Disease Relevance 0 Pain Relevance 0.12
Both S3 and S4 were co-localized with ezrin in perinodal processes.


Localization (localized) of ezrin
3) Confidence 0.18 Published 2003 Journal BMC Neurosci Section Abstract Doc Link PMC293377 Disease Relevance 0 Pain Relevance 0.15

General Comments

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