INT175071

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Context Info
Confidence 0.12
First Reported 2003
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Ezr) cytoplasm (Ezr) cytosol (Ezr)
cytoskeletal protein binding (Ezr) structural molecule activity (Ezr) nucleolus (Ezr)
Anatomy Link Frequency
lateral 1
band 1
basal cell 1
Ezr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Sciatic nerve 18 41.56 Quite Low
sodium channel 6 34.48 Quite Low
anesthesia 9 5.00 Very Low Very Low Very Low
ketamine 6 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Nav1.6 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Nav1.2 1 5.00 Very Low Very Low Very Low
Action potential 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 20 69.40 Quite High
Neuroblastoma 1 8.16 Low Low
Injury 9 5.00 Very Low Very Low Very Low
Ganglion Cysts 9 5.00 Very Low Very Low Very Low
Hypothermia 6 5.00 Very Low Very Low Very Low
Proliferative Vitreoretinopathy 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this context, the ERM proteins may function as adaptors that couple syndecans to cytoskeletal proteins since S2 has been shown to interact with ezrin through a motif conserved in the others syndecans [30,31].
ezrin Binding (interact) of
1) Confidence 0.12 Published 2003 Journal BMC Neurosci Section Body Doc Link PMC293377 Disease Relevance 0.07 Pain Relevance 0
Due to the distinct locations of these two PDZ proteins within the RPE, CD81 must be involved in at least two different molecular complexes, one in the microvilli associated with EBP50/Ezrin and the other associated with Sap97 on the lateral and basal cell surfaces.
Ezrin Binding (associated) of in basal cell
2) Confidence 0.12 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2610370 Disease Relevance 0 Pain Relevance 0
Since there is a strong association between EBP50 and Ezrin [33,36], we also probed the immunoprecipitated proteins with anti-Ezrin antibodies, observing a strong band (Figure 2C).
Ezrin Binding (association) of in band
3) Confidence 0.12 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2610370 Disease Relevance 0 Pain Relevance 0
Due to the distinct locations of these two PDZ proteins within the RPE, CD81 must be involved in at least two different molecular complexes, one in the microvilli associated with EBP50/Ezrin and the other associated with Sap97 on the lateral and basal cell surfaces.
Ezrin Binding (associated) of in lateral
4) Confidence 0.04 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2610370 Disease Relevance 0 Pain Relevance 0

General Comments

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