INT175110

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 2003
Last Reported 2003
Negated 1
Speculated 2
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.38
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (LCN6)
Anatomy Link Frequency
testis 3
LCN6 (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 10 83.00 Quite High
Analgesic 5 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Embryonal Carcinoma 15 84.84 Quite High
Apoptosis 10 60.36 Quite High
Bacterial Respiratory Disease 10 50.80 Quite High
Reprotox - General 1 5 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Dissociative Disorders 5 5.00 Very Low Very Low Very Low
Body Weight 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ligand binding properties of human LCN6 may be affected by the lack of the cysteine near the C-terminus that is strongly conserved in lipocalins.
Spec (may) Regulation (affected) of LCN6
1) Confidence 0.45 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC293424 Disease Relevance 0 Pain Relevance 0
Based on the similarity of the predicted human LCN6 structure to that of mouse Mup1 previously determined by X-ray diffraction [14], a model of the human LCN6 was calculated (Fig. 4).
Regulation (calculated) of LCN6
2) Confidence 0.45 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC293424 Disease Relevance 0 Pain Relevance 0
Unlike the rodent Lcn5, monkey LCN6 mRNA levels appear to be little regulated by androgen and unlike mouse Lcn8, monkey LCN6 regulation by other testis factors, appears minimal 6 days after testis removal.
Regulation (regulation) of LCN6 in testis
3) Confidence 0.27 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC293424 Disease Relevance 0.17 Pain Relevance 0
Unlike the rodent Lcn5, monkey LCN6 mRNA levels appear to be little regulated by androgen and unlike mouse Lcn8, monkey LCN6 regulation by other testis factors, appears minimal 6 days after testis removal.
Neg (little) Regulation (regulated) of LCN6 in testis
4) Confidence 0.27 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC293424 Disease Relevance 0.13 Pain Relevance 0
To determine if LCN6 is regulated by testosterone as reported for Lcn5 in the mouse [56] or testis factors as reported for mouse Lcn8, RNA was obtained from caput, corpus and cauda epididymis of rhesus monkeys that were sham operated, castrated 6 days and castrated but given a single injection of 400 mg testosterone enanthate immediately following testis removal (Fig. 6).
Spec (determine) Regulation (regulated) of LCN6 in testis
5) Confidence 0.27 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC293424 Disease Relevance 0.08 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox