INT17528

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Context Info
Confidence 0.28
First Reported 1981
Last Reported 1991
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.28
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Prl, Gh) cytosol (Gh) signal transduction (Gh)
mitochondrion (Gh) extracellular space (Gh) plasma membrane (Gh)
Anatomy Link Frequency
plasma 1
Prl (Rattus norvegicus)
Gh (Mus musculus)
Pain Link Frequency Relevance Heat
Clonidine 1 100.00 Very High Very High Very High
opiate 3 99.98 Very High Very High Very High
narcan 6 96.86 Very High Very High Very High
dexamethasone 1 89.92 High High
depression 3 87.88 High High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Acromegaly 3 99.44 Very High Very High Very High
Eating Disorder 8 88.40 High High
Depression 3 87.88 High High
Congenital Anomalies 2 81.20 Quite High
Appetite Loss 1 79.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Naloxone also interfered with the lowering effects of CB154 and GH and PRL serum levels, pointing to the existence of an interaction between dopaminergic and opiate control of GH and PRL secretion in acromegaly.
PRL Regulation (control) of GH associated with acromegaly, narcan and opiate
1) Confidence 0.28 Published 1981 Journal Med. Biol. Section Abstract Doc Link 7266088 Disease Relevance 0.27 Pain Relevance 0.46
Bulimics, however, have a normal GH response to clonidine, a nonblunted TSH response to TRH, low basal prolactin (PRL) levels, and may have an exaggerated PRL response to TRH.
PRL Regulation (response) of GH associated with clonidine
2) Confidence 0.03 Published 1989 Journal Biol. Psychiatry Section Abstract Doc Link 2521454 Disease Relevance 1.01 Pain Relevance 0.28
The effects of intranasal and iv administration of His-D-Trp-Ala-Trp-D-Phe-LysNH2 (GHRP) on plasma GH, PRL, LH, FSH, TSH, cortisol, insulin, IGF-I as well as GHRH-like immunoreactivity (LI) levels were examined in 6 healthy male subjects.
PRL Spec (examined) Regulation (effects) of GH in plasma
3) Confidence 0.00 Published 1991 Journal Endocrinol. Jpn. Section Abstract Doc Link 1915110 Disease Relevance 0 Pain Relevance 0

General Comments

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