INT175424

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Context Info
Confidence 0.05
First Reported 2003
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TSC1) embryo development (TSC1) protein complex (TSC1)
cytoplasm (TSC1)
Anatomy Link Frequency
colon 2
TSC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 125 100.00 Very High Very High Very High
Colon Cancer 22 100.00 Very High Very High Very High
Nicotine Addiction 44 81.92 Quite High
Lung Cancer 76 77.72 Quite High
Genomic Instability 9 60.12 Quite High
Congenital Anomalies 20 57.20 Quite High
Disease 13 47.68 Quite Low
Metastasis 6 11.96 Low Low
Non-small-cell Lung Cancer 12 5.00 Very Low Very Low Very Low
Adenocarcinoma 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to being markers of carcinogen exposure, it is possible that these adducts may directly alter regulation of transcription of tumor suppressor or oncogenes [74].
Regulation (regulation) of Transcription (transcription) of tumor suppressor associated with cancer
1) Confidence 0.05 Published 2003 Journal Respir Res Section Body Doc Link PMC314397 Disease Relevance 0.95 Pain Relevance 0
Previous studies from our laboratory have identified a number of miRNAs that were deregulated in colon cancer cell lines due to the deletion of the p53 tumor suppressor gene.
Regulation (deregulated) of Transcription (deletion) of tumor suppressor in colon associated with cancer and colon cancer
2) Confidence 0.04 Published 2006 Journal Biomark Insights Section Abstract Doc Link PMC2134920 Disease Relevance 0.43 Pain Relevance 0

General Comments

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