INT175448

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Context Info
Confidence 0.03
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.39
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lymphocytes 1
synapses 1
neutrophils 1
Tchol1 (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 23 99.58 Very High Very High Very High
Anterior cingulate cortex 31 99.32 Very High Very High Very High
Inflammation 64 96.44 Very High Very High Very High
nMDA receptor 23 94.16 High High
cytokine 26 89.12 High High
Inflammatory response 2 71.12 Quite High
Pyramidal cell 3 59.88 Quite High
fibrosis 112 21.80 Low Low
Glutamate 2 12.00 Low Low
metalloproteinase 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aspergillus Infection 44 97.88 Very High Very High Very High
INFLAMMATION 59 96.44 Very High Very High Very High
Pneumonia 10 93.80 High High
Acatalasemia 6 84.52 Quite High
Injury 7 84.12 Quite High
Disease 5 79.76 Quite High
Asthma 7 78.08 Quite High
Lung Injury 6 74.64 Quite High
Hypersensitivity 35 67.44 Quite High
Sprains And Strains 22 53.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One possible mechanism of enhanced LTP in the wild mice is increased total NMDA current in ACC synapses.
Positive_regulation (increased) of total in synapses associated with long-term potentiation and anterior cingulate cortex
1) Confidence 0.03 Published 2009 Journal Mol Brain Section Body Doc Link PMC2694782 Disease Relevance 0 Pain Relevance 0.49
Analysis of the cellular fraction of BAL showed that both Balb/c and C57BL/6 mice had increased and similar total cell numbers after sensitization and challenge with Af (Figure 3A) in comparison with naïve controls.
Positive_regulation (increased) of total associated with aspergillus infection
2) Confidence 0.02 Published 2003 Journal Respir Res Section Body Doc Link PMC314399 Disease Relevance 0.96 Pain Relevance 0.08
However, the elevations of total cell numbers, lymphocytes and neutrophils were prolonged in acatalasemic mice compared with wild-type mice and showed significant difference at 14 days between wild-type mice and acatalasemic mice (Table 2), suggesting sustained inflammation in acatalasemic mice after bleomycin administration.
Positive_regulation (elevations) of total in neutrophils associated with inflammation
3) Confidence 0.01 Published 2010 Journal Respir Res Section Body Doc Link PMC3022724 Disease Relevance 0.72 Pain Relevance 0.33
However, the elevations of total cell numbers, lymphocytes and neutrophils were prolonged in acatalasemic mice compared with wild-type mice and showed significant difference at 14 days between wild-type mice and acatalasemic mice (Table 2), suggesting sustained inflammation in acatalasemic mice after bleomycin administration.
Positive_regulation (elevations) of total in lymphocytes associated with inflammation
4) Confidence 0.00 Published 2010 Journal Respir Res Section Body Doc Link PMC3022724 Disease Relevance 0.72 Pain Relevance 0.33

General Comments

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