INT175450

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Context Info
Confidence 0.25
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.69
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Cel) extracellular space (Cel) extracellular region (Cel)
Golgi apparatus (Cel) protein complex (Cel) cytoplasm (Cel)
Anatomy Link Frequency
nasal 2
lung 2
Cel (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 123 87.80 High High
imagery 28 84.80 Quite High
medulla 1 76.32 Quite High
Central nervous system 23 71.04 Quite High
antagonist 10 68.48 Quite High
Inflammatory response 3 59.04 Quite High
Inflammatory stimuli 1 54.16 Quite High
adenocard 36 39.12 Quite Low
cytokine 22 5.00 Very Low Very Low Very Low
agonist 21 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aspergillus Infection 44 99.80 Very High Very High Very High
Immunization 21 99.76 Very High Very High Very High
INFLAMMATION 114 87.80 High High
Lung Injury 35 85.96 High High
Infection 32 79.76 Quite High
Respiratory Syncytial Virus 94 79.36 Quite High
Multiple Sclerosis 53 70.80 Quite High
Influenza Virus Infection 2 57.60 Quite High
Disease 31 56.76 Quite High
Hypersensitivity 36 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This was accompanied by an increase in lung vascular permeability as reflected by enhanced BAL protein levels in A2AR-deficient mice and a decrease in overall lung function, which was manifested by a decrease in arterial blood oxygen tension as compared to wild-type mice.
Positive_regulation (enhanced) of Gene_expression (levels) of BAL protein in lung
1) Confidence 0.25 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1088279 Disease Relevance 0.62 Pain Relevance 0.24
Thus, sensitization and challenge with Af markedly increased SP-D protein content in the SA BAL fraction of both Balb/c and C57BL/6 mice, however the latter show a distinctly greater capability to produce SP-D in response to allergen challenge.
Positive_regulation (increased) of Gene_expression (fraction) of BAL associated with aspergillus infection
2) Confidence 0.15 Published 2003 Journal Respir Res Section Body Doc Link PMC314399 Disease Relevance 0.33 Pain Relevance 0
Finally, nasal immunization with N SRS generated strong local and systemic Ab responses, including a massive anti-N IgA Ab production in BAL.
Positive_regulation (generated) of Gene_expression (production) of BAL in nasal associated with immunization
3) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2262139 Disease Relevance 1.05 Pain Relevance 0.07
After 1 h, Gf CEL were detectable with circumscribed subtle parenchymal signal enhancement, and developed further within 24 h (figure 2A, arrowheads).
Positive_regulation (enhancement) of Gene_expression (detectable) of Gf CEL
4) Confidence 0.04 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2978145 Disease Relevance 0.70 Pain Relevance 0.38

General Comments

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