INT175457

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Context Info
Confidence 0.10
First Reported 2003
Last Reported 2003
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lung 2
Colec12 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 20 99.32 Very High Very High Very High
cytokine 14 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 35 99.68 Very High Very High Very High
INFLAMMATION 21 99.32 Very High Very High Very High
Aspergillus Infection 44 67.52 Quite High
Sprains And Strains 16 7.92 Low Low
Asthma 5 5.00 Very Low Very Low Very Low
Eosinophilia 3 5.00 Very Low Very Low Very Low
Airway Obstruction 2 5.00 Very Low Very Low Very Low
Rhinitis 2 5.00 Very Low Very Low Very Low
Pneumonia 2 5.00 Very Low Very Low Very Low
Immunization 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since changes in mRNA expression were not proportional to those in protein expression (an approximately two fold increase in SP-D mRNA accompanied a nearly 20 fold enhancement in SP-D protein), we speculate that in addition to transcriptional regulation, metabolism of this lung collectin may also be significantly affected during allergic inflammation and a reduced recycling or an increased half life may contribute to its accumulation [30].
Spec (may) Regulation (affected) of Localization (metabolism) of collectin in lung associated with inflammation and hypersensitivity
1) Confidence 0.10 Published 2003 Journal Respir Res Section Body Doc Link PMC314399 Disease Relevance 0.73 Pain Relevance 0.14

General Comments

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