INT175471

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Context Info
Confidence 0.73
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
annulus 2
Gbp1 (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 2 8.64 Low Low
Somatostatin 8 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 114 96.12 Very High Very High Very High
Acute Myocarditis 41 91.04 High High
Apoptosis 16 88.12 High High
Necrosis 8 87.60 High High
Toxicity 4 51.12 Quite High
Body Weight 4 43.44 Quite Low
Retinoblastoma 12 28.16 Quite Low
Heart Disease 2 11.96 Low Low
Injury 1 7.68 Low Low
Dilated Cardiomyopathy 2 6.20 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our analysis showed that mitogen-activated protein kinase p38 (also know as p38, p38 MPA kinase or MPAK14) was significantly upregulated in senescent compared to non-senescent annulus cells.
Localization (kinase) of MPA in annulus
1) Confidence 0.73 Published 2010 Journal BMC Biotechnol Section Body Doc Link PMC2828399 Disease Relevance 0.41 Pain Relevance 0
Our analysis showed that mitogen-activated protein kinase p38 (also know as p38, p38 MPA kinase or MPAK14) was significantly upregulated in senescent compared to non-senescent annulus cells.
Localization (kinase) of MPA in annulus
2) Confidence 0.73 Published 2010 Journal BMC Biotechnol Section Body Doc Link PMC2828399 Disease Relevance 0.41 Pain Relevance 0
In virus yield assays, MPA and ribavirin (both at 100 ?
Localization (ribavirin) of MPA
3) Confidence 0.13 Published 2003 Journal BMC Microbiol Section Body Doc Link PMC317291 Disease Relevance 0.23 Pain Relevance 0

General Comments

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