INT175522

Context Info Confidence 0.02 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.73 Pain Relevance 0

kinase activity (Map3k15) cellular_component (Map3k15)

Map3k15 (Mus musculus)

Pain Link Frequency Relevance Heat Bile 1 5.00 palliative 1 5.00 metalloproteinase 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Severe Combined Immunodeficiency 7 97.92 Liver Cancer 12 95.44 Cancer 72 94.96 Apoptosis 39 83.36 Hepatocellular Cancer 36 50.00 Death 7 5.00 Cirrhosis 5 5.00 Metastasis 4 5.00 Disease 4 5.00 Cleidocranial Dysplasia 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

To test the neoplastic behaviour of activated MEK1 cells in vivo, mock-transfected pUSE-9 and pUSE-12 and activated MEK1-transfected pMEK1-15 and pMEK1-17 clones were injected in the flanks of SCID mice.

Positive_regulation (activated) of pMEK1-15 associated with severe combined immunodeficiency

1) Confidence 0.02 Published 2003 Journal BMC Gastroenterol Section Body Doc Link PMC317301 Disease Relevance 0.73 Pain Relevance 0

General Comments

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