INT175527

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.31
First Reported 2003
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.41
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Map2k1) cytoplasm (Map2k1) cytosol (Map2k1)
cell proliferation (Map2k1) mitosis (Map2k1) cell motility (Map2k1)
Map2k1 (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 2 74.32 Quite High
cytokine 10 69.04 Quite High
tolerance 1 51.84 Quite High
palliative 5 50.00 Quite Low
Inflammation 10 5.00 Very Low Very Low Very Low
imagery 10 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Kinase C 5 5.00 Very Low Very Low Very Low
Analgesic 4 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 39 97.72 Very High Very High Very High
Shock 1 97.12 Very High Very High Very High
Lymphatic System Cancer 1 89.04 High High
Hepatocellular Cancer 72 88.92 High High
Hypoxia 3 87.64 High High
Apoptosis 103 87.24 High High
Cancer 180 86.16 High High
Adhesions 3 83.32 Quite High
Benign Prostatic Hypertrophy 3 75.00 Quite High
Liver Cancer 24 74.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study we are unable to co-localize activated MAPK and MEK1/2.
Localization (localize) of MEK1
1) Confidence 0.31 Published 2003 Journal BMC Gastroenterol Section Body Doc Link PMC317301 Disease Relevance 0.56 Pain Relevance 0
Immuno-histochemistry was used to localize phosphorylated MAPK and MEK1/2 in the tissues. 3-(4,5-Dimethylthiazol-2-y1)-2,5-diphenyltetrazolium bromide (MTT) assay and ELISA were used to determine cell viability and cell proliferation.
Localization (localize) of MEK1
2) Confidence 0.31 Published 2003 Journal BMC Gastroenterol Section Abstract Doc Link PMC317301 Disease Relevance 0.62 Pain Relevance 0
These, identified by microarray include, PI3-K, JAK2, JAK3, STAT3, Grb2, IRS, and PLCgamma1, Rho-GTPase activating protein (RAB35), kinases (MEK kinase 1 and 4, PKC, MLCK, cyclin G-associated kinase, EphA1, JNK kinase, MAP kinase 1), phosphatases (meprin, PTPK, protein phosphatase 2 subunit), and heat shock proteins (Hsp60 precursor), as well as SOCS (25).
Localization (cyclin) of MAP kinase 1 associated with shock
3) Confidence 0.10 Published 2005 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1297502 Disease Relevance 0.19 Pain Relevance 0.09
MAPKK MAPK kinase
Localization (kinase) of MAPKK
4) Confidence 0.04 Published 2004 Journal Cell Commun Signal Section Body Doc Link PMC449737 Disease Relevance 1.04 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox