INT175552

Context Info Confidence 0.01 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 0.89 Pain Relevance 0.33

helicase activity (UPF1) DNA binding (UPF1) cytoplasm (UPF1) signal transducer activity (CASR) cytosol (UPF1) RNA binding (UPF1)

CASR (Homo sapiens) UPF1 (Homo sapiens)

Pain Link Frequency Relevance Heat Chronic pancreatitis 39 99.76 Lasting pain 1 5.00 fibrosis 1 5.00

Disease Link Frequency Relevance Heat Pancreatitis 69 99.76 Disease 14 73.40 Hypercalcemia 33 70.16 Disorders Of Creatine Metabolism 2 5.00 Pain 1 5.00 Cystic Fibrosis 1 5.00 Myocardial Infarction 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations Background

calcium sensing receptor Binding (associated) of mutation associated with chronic pancreatitis

1) Confidence 0.01 Published 2003 Journal BMC Gastroenterol Section Title Doc Link PMC317302 Disease Relevance 0.89 Pain Relevance 0.33

General Comments

This test has worked.